[CDATA[/* >*/, Facts about OTC redness-relief eye drops and nasal decongestant sprays. If a child accidentally swallows these eye drops or nasal decongestant spray, call the toll-free Poison Help Line (1-800-222-1222) and seek emergency medical care immediately. Something as seemingly simple as a small bottle of non-prescription eye drops can pack a big wallop to small kids and unsuspecting victims of malicious poisoning. When used, “only as directed,” tetrahydrozoline is an effective medication which shrinks blood vessels thus alleviating reddened “bloodshot” eyes. literature, Reliable, up-to-date health Drug Safety and Availability, Recalls, Market Withdrawals and Safety Alerts, Information about Nitrosamine Impurities in Medications, Medication Errors Related to CDER-Regulated Drug Products, Postmarket Drug Safety Information for Patients and Providers, Risk Evaluation and Mitigation Strategies | REMS, Multistate outbreak of fungal meningitis and other infections, FDA Drug Safety Communication: Serious adverse events from accidental ingestion by children of over-the-counter eye drops and nasal sprays, Comunicado de la FDA sobre la seguridad de los medicamentos: Sucesos adversos graves resultantes de ingestión accidental por niños de colirios (gotas para los ojos) y aerosoles nasales de venta libre. The cases of accidental ingestion reviewed by FDA occurred in children 5 years of age and younger (see Data Summary below). NLM Lindberg-King Lecture & Scientific Symposium on September 1, 2021. Search Tool. color: #f9e4bb; Serious harm may result from accidentally swallowing over-the-counter (available without a prescription) redness-relief eye drops or nasal decongestant sprays containing the active ingredients tetrahydrozoline, oxymetazoline, or naphazoline. These products are safe when used in the eyes or the nose as directed, but if ingested, they may cause serious and life-threatening adverse events. This all-day event â Science, Society and the Legacy of Donald AB Lindberg, MD will be in honor of Dr. Lindberg who passed away in August 2019. Consumers should store these products out of reach of children at all times. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. “Revenge is Best Served Cold,” a CSI: Crime Scene Investigation episode first aired in 2002 involved a case of the murder of a high stakes poker player. 15 Nov 2006. If a child accidentally swallows these eye drops or nasal decongestant spray, call the toll-free Poison Help Line (1-800-222-1222) and seek emergency medical care immediately. Fifty-three cases reported hospitalization due to symptoms including nausea, vomiting, lethargy, tachycardia, decreased respiration, bradycardia, hypotension, hypertension, sedation, somnolence, mydriasis, stupor, hypothermia, drooling, and coma. Other drugs which are similar to tetrahydrozoline used in eye drops and nasal decongestants include xylometazoline, oxymetazoline and naphazoline. These products contain the active ingredients tetrahydrozoline, oxymetazoline, or naphazoline. Both 0.02% naphazoline HCI and 0.05% tetrahydrozoline HCI significantly reduced baseline redness after a single use (Part I); however, naphazoline produced significantly more whitening than did tetrahydrozoline. 2010 Jan-Feb. 19709378. “Visine® Prank Leads to Day in Court” Milwaukee Journal Sentinel. Symptoms reported in both children and adults who have swallowed some of these eye care products either by accident or via malicious activity include marked drowsiness, low blood pressure, slowed heart rate, and possibly even coma and impaired breathing. So is all this reporting of tetrahydrozoline toxicity fact or fiction? Report side effects or medication errors from the use of these eye drops or nasal decongestant sprays to the FDA MedWatch program, using the information in the "Contact FDA" box at the bottom of this page. Only naphazoline retained its whitening ability after ten days (Part II). Central nervous system depression following accidental ingestion of Visine eye drops. Research groups at NCBI investigate a wide range of topics in computational biology and information science. Additionally, two literature reports indicate that a 1.5 mL to 3 mL volume produced severe adverse events such as central nervous system and respiratory depression, and bradycardia in a 25-day-old infant and a 2-year-old child.2,3, Afrin No Drip Severe Congestion Nasal Spray, Walgreens Redness Reliever Advanced Eye Ophthalmic Solution, All Clear AR Maximum Strength Ophthalmic Solution, Afrin No Drip Sinus Extra Moisturizing Nasal Spray, Equaline 12 Hour Extra Moisturizing Nasal Spray, Leader Eye Drops Regular Formula Ophthalmic Solution, Maximum Strength Nasal Decongestant Nasal Spray. *The proposed rule also covers products that contain xylometazoline; however products containing xylometazoline are not currently marketed. .benefit { Help guide the continuing implementation of NLM's strategic plan through 2027. Quantities as low as ½ to 1½ teaspoonfuls (approximately 1/6 to ½ of a half ounce bottle) have caused pronounced reactions in small children. 14 Dec 2007. The National Library of Medicine (NLM), on the NIH campus in Bethesda, Maryland, is the world's largest biomedical library and the developer of electronic information services that delivers data to millions of scientists, health professionals and members of the public around the globe, every day. A comparative kinetic and mechanistic study between tetrahydrozoline and naphazoline toward photogenerated reactive oxygen species. Research in the NCBI Computational Biology Branch focuses on a broad range of topics in molecular biomedicine. “Gal’s Toxic Visine® Tea” New York Post. If this is your first time here, you must check out, Tetrahydrozoline (Visine®) does more than just “get the red out®”, Substitute’s Coffee Spiked with Substance, You might say the Illinois Poison Center is the Antidote to Unnecessary Health Care Costs, Tell Us About Your IPC Helpline Experience. Welcome to the Illinois Poison Center Blog.
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